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Primary α-tertiary amine synthesis via α-C–H functionalization
A quinone-mediated general synthetic platform for the construction of primary α-tertiary amines from abundant primary α-branched amine starting materials is described. This procedure pivots on the efficient in situ generation of reactive ketimine intermediates and subsequent reaction with carbon-cen...
Autores principales: | Vasu, Dhananjayan, Fuentes de Arriba, Angel L., Leitch, Jamie A., de Gombert, Antoine, Dixon, Darren J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429468/ https://www.ncbi.nlm.nih.gov/pubmed/30996928 http://dx.doi.org/10.1039/c8sc05164j |
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