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Loss of SR-BI Down-Regulates MITF and Suppresses Extracellular Vesicle Release in Human Melanoma

Melanoma is a skin tumor with a high tendency for metastasis and thus is one of the deadliest cancers worldwide. Here, we investigated the expression of the scavenger receptor class B type 1 (SR-BI), a high-density lipoprotein (HDL) receptor, and tested for its role in melanoma pigmentation as well...

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Detalles Bibliográficos
Autores principales: Kinslechner, Katharina, Schütz, Birgit, Pistek, Martina, Rapolter, Philipp, Weitzenböck, Hans P., Hundsberger, Harald, Mikulits, Wolfgang, Grillari, Johannes, Röhrl, Clemens, Hengstschläger, Markus, Stangl, Herbert, Mikula, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429474/
https://www.ncbi.nlm.nih.gov/pubmed/30823658
http://dx.doi.org/10.3390/ijms20051063