Cross-Species Analysis of Glycosaminoglycan Binding Proteins Reveals Some Animal Models Are “More Equal” than Others

Glycosaminoglycan (GAG) mimetics are synthetic or semi-synthetic analogues of heparin or heparan sulfate, which are designed to interact with GAG binding sites on proteins. The preclinical stages of drug development rely on efficacy and toxicity assessment in animals and aim to apply these findings...

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Detalles Bibliográficos
Autores principales: Boittier, Eric D., Gandhi, Neha S., Ferro, Vito, Coombe, Deirdre R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429508/
https://www.ncbi.nlm.nih.gov/pubmed/30845788
http://dx.doi.org/10.3390/molecules24050924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429508/
https://www.ncbi.nlm.nih.gov/pubmed/30845788
http://dx.doi.org/10.3390/molecules24050924

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