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Chronic myelomonocytic leukemia as a transformation from polycythemia vera

The hallmark of Polycythemia vera (PV) is the presence of JAK2(V617F) mutation and increased RBC mass. Chronic myelomonocytic leukemia (CMML) is defined as persistent blood absolute monocyte count (AMC) >/= 1 × 10(9)/L for at least 3 months with myeloid cell dysplasia. Few cases of evolved CMML f...

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Detalles Bibliográficos
Autores principales: Andrei, Mirela, Pandey, Anita, Avezbakiyev, Boris, Wang, Jen Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429537/
https://www.ncbi.nlm.nih.gov/pubmed/30949429
http://dx.doi.org/10.1016/j.lrr.2019.03.004