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Synthesis, Characterization, and Anticancer Activities Evaluation of Compounds Derived from 3,4-Dihydropyrimidin-2(1H)-one

3,4-dihydropyrimidin-2(1H)-one compounds (DHPMs) possess extensive biological activities and are mainly prepared via Biginelli reaction and N-alkylation. In the present study, selective alkylation of N(1) was investigated by using tetrabutylammonium hydroxide. In vitro cytotoxicity study on all synt...

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Detalles Bibliográficos
Autores principales: Liu, Ye, Liu, Jiaqi, Zhang, Renmei, Guo, Yan, Wang, Hongbo, Meng, Qingguo, Sun, Yuan, Liu, Zongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429579/
https://www.ncbi.nlm.nih.gov/pubmed/30832453
http://dx.doi.org/10.3390/molecules24050891