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Synthesis, Characterization, and Anticancer Activities Evaluation of Compounds Derived from 3,4-Dihydropyrimidin-2(1H)-one
3,4-dihydropyrimidin-2(1H)-one compounds (DHPMs) possess extensive biological activities and are mainly prepared via Biginelli reaction and N-alkylation. In the present study, selective alkylation of N(1) was investigated by using tetrabutylammonium hydroxide. In vitro cytotoxicity study on all synt...
Autores principales: | Liu, Ye, Liu, Jiaqi, Zhang, Renmei, Guo, Yan, Wang, Hongbo, Meng, Qingguo, Sun, Yuan, Liu, Zongliang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429579/ https://www.ncbi.nlm.nih.gov/pubmed/30832453 http://dx.doi.org/10.3390/molecules24050891 |
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