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Challenges and clinical relevance of molecular detection of Bordetella pertussis in South Africa

BACKGROUND: We assessed the utility of a multi-target, real-time PCR assay for Bordetella pertussis detection and diagnosis in patients with severe respiratory illness (SRI), influenza-like illness (ILI), and asymptomatic controls. METHODS: Real-time PCR detection of IS481, pIS1001, hIS1001 and ptxS...

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Detalles Bibliográficos
Autores principales: Moosa, Fahima, du Plessis, Mignon, Wolter, Nicole, Carrim, Maimuna, Cohen, Cheryl, von Mollendorf, Claire, Walaza, Sibongile, Tempia, Stefano, Dawood, Halima, Variava, Ebrahim, von Gottberg, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429695/
https://www.ncbi.nlm.nih.gov/pubmed/30898099
http://dx.doi.org/10.1186/s12879-019-3869-7