Structure–activity relationships in a series of antiplasmodial thieno[2,3-b]pyridines

BACKGROUND: Malaria is one of the most prevalent tropical infectious diseases. Since recently cases of artemisinin resistance were reported, novel anti-malarial drugs are required which differ from artemisinins in structure and biological target. The plasmodial glycogen synthase kinase-3 (PfGSK-3) w...

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Detalles Bibliográficos
Autores principales: Masch, Andreas, Nasereddin, Abed, Alder, Arne, Bird, Megan J., Schweda, Sandra I., Preu, Lutz, Doerig, Christian, Dzikowski, Ron, Gilberger, Tim W., Kunick, Conrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429710/
https://www.ncbi.nlm.nih.gov/pubmed/30898128
http://dx.doi.org/10.1186/s12936-019-2725-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429710/
https://www.ncbi.nlm.nih.gov/pubmed/30898128
http://dx.doi.org/10.1186/s12936-019-2725-y

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