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Evidence for an association of gut microbial Clostridia with brain functional connectivity and gastrointestinal sensorimotor function in patients with irritable bowel syndrome, based on tripartite network analysis

BACKGROUND AND AIMS: Evidence from preclinical and clinical studies suggests that interactions among the brain, gut, and microbiota may affect the pathophysiology of irritable bowel syndrome (IBS). As disruptions in central and peripheral serotonergic signaling pathways have been found in patients w...

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Detalles Bibliográficos
Autores principales: Labus, Jennifer S., Osadchiy, Vadim, Hsiao, Elaine Y., Tap, Julien, Derrien, Muriel, Gupta, Arpana, Tillisch, Kirsten, Le Nevé, Boris, Grinsvall, Cecilia, Ljungberg, Maria, Öhman, Lena, Törnblom, Hans, Simren, Magnus, Mayer, Emeran A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429755/
https://www.ncbi.nlm.nih.gov/pubmed/30898151
http://dx.doi.org/10.1186/s40168-019-0656-z