Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer’s disease

BACKGROUND: Alzheimer’s disease is a progressive neurodegenerative disorder that is hypothesized to involve epigenetic dysfunction. Previous studies of DNA modifications in Alzheimer’s disease have been unable to distinguish between DNA methylation and DNA hydroxymethylation. DNA hydroxymethylation...

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Detalles Bibliográficos
Autores principales: Smith, Adam R., Smith, Rebecca G., Pishva, Ehsan, Hannon, Eilis, Roubroeks, Janou A. Y., Burrage, Joe, Troakes, Claire, Al-Sarraj, Safa, Sloan, Carolyn, Mill, Jonathan, van den Hove, Daniel L., Lunnon, Katie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429761/
https://www.ncbi.nlm.nih.gov/pubmed/30898171
http://dx.doi.org/10.1186/s13148-019-0636-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429761/
https://www.ncbi.nlm.nih.gov/pubmed/30898171
http://dx.doi.org/10.1186/s13148-019-0636-y

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