Genome-wide CRISPR screen reveals PSMA6 to be an essential gene in pancreatic cancer cells

BACKGROUND: Despite its relatively low incidence, pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer deaths because of the aggressive growth/metastasis of the tumor, the lack of early symptoms, and the poor treatment options. Basic research to identify potential therapeutic targets...

Descripción completa

Detalles Bibliográficos
Autores principales: Bakke, Jesse, Wright, William C., Zamora, Anthony E., Oladimeji, Peter, Crawford, Jeremy Chase, Brewer, Christopher T., Autry, Robert J., Evans, William E., Thomas, Paul G., Chen, Taosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429770/
https://www.ncbi.nlm.nih.gov/pubmed/30898113
http://dx.doi.org/10.1186/s12885-019-5455-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429770/
https://www.ncbi.nlm.nih.gov/pubmed/30898113
http://dx.doi.org/10.1186/s12885-019-5455-1

Ejemplares similares