Interaction between the BAG1S isoform and HSP70 mediates the stability of anti-apoptotic proteins and the survival of osteosarcoma cells expressing oncogenic MYC

BACKGROUND: The oncoprotein MYC has the dual capacity to drive cell cycle progression or induce apoptosis, depending on the cellular context. BAG1 was previously identified as a transcriptional target of MYC that functions as a critical determinant of this cell fate decision. The BAG1 protein is exp...

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Detalles Bibliográficos
Autores principales: Gennaro, Victoria J., Wedegaertner, Helen, McMahon, Steven B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429775/
https://www.ncbi.nlm.nih.gov/pubmed/30902071
http://dx.doi.org/10.1186/s12885-019-5454-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429775/
https://www.ncbi.nlm.nih.gov/pubmed/30902071
http://dx.doi.org/10.1186/s12885-019-5454-2

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