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Tramadol and the risk of seizure: nested case-control study of US patients with employer-sponsored health benefits

OBJECTIVES: Tramadol is a widely prescribed analgesic that influences both opioid and monoamine neurotransmission. While seizures have been reported with its use, the risk in clinical practice has not been well characterised. We examined risk of seizure with tramadol relative to codeine, a comparabl...

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Detalles Bibliográficos
Autores principales: Morrow, Richard L, Dormuth, Colin R, Paterson, Michael, Mamdani, Muhammad M, Gomes, Tara, Juurlink, David N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429854/
https://www.ncbi.nlm.nih.gov/pubmed/30872555
http://dx.doi.org/10.1136/bmjopen-2018-026705