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Chalcone derivatives: synthesis, in vitro and in vivo evaluation of their anti-anxiety, anti-depression and analgesic effects

Anxiety disorders, depression and pain are highly prevalent pathologies. Their pharmacotherapy is associated with unwanted side effects; hence there is a clinical need to develop more effective drugs with fewer adverse reactions. Chalcones are one of the major classes of naturally occurring compound...

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Detalles Bibliográficos
Autores principales: Higgs, Josefina, Wasowski, Cristina, Marcos, Alejandra, Jukič, Marko, Paván, Carlos Humberto, Gobec, Stanislav, de Tezanos Pinto, Felicitas, Colettis, Natalia, Marder, Mariel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430037/
https://www.ncbi.nlm.nih.gov/pubmed/30949609
http://dx.doi.org/10.1016/j.heliyon.2019.e01376