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Chalcone derivatives: synthesis, in vitro and in vivo evaluation of their anti-anxiety, anti-depression and analgesic effects
Anxiety disorders, depression and pain are highly prevalent pathologies. Their pharmacotherapy is associated with unwanted side effects; hence there is a clinical need to develop more effective drugs with fewer adverse reactions. Chalcones are one of the major classes of naturally occurring compound...
Autores principales: | Higgs, Josefina, Wasowski, Cristina, Marcos, Alejandra, Jukič, Marko, Paván, Carlos Humberto, Gobec, Stanislav, de Tezanos Pinto, Felicitas, Colettis, Natalia, Marder, Mariel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430037/ https://www.ncbi.nlm.nih.gov/pubmed/30949609 http://dx.doi.org/10.1016/j.heliyon.2019.e01376 |
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