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Acceleration of Fracture Healing by Overexpression of Basic Fibroblast Growth Factor in the Mesenchymal Stromal Cells

In this study, we engineered mesenchymal stem cells (MSCs) to over‐express basic fibroblast growth factor (bFGF) and evaluated its effects on fracture healing. Adipose‐derived mouse MSCs were transduced to express bFGF and green fluorescence protein (ADSC(bFGF)‐GFP). Closed‐femoral fractures were pe...

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Detalles Bibliográficos
Autores principales: Zhang, Hongliang, Kot, Alexander, Lay, Yu‐An E., Fierro, Fernando A., Chen, Haiyan, Lane, Nancy E., Yao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430058/
https://www.ncbi.nlm.nih.gov/pubmed/28792122
http://dx.doi.org/10.1002/sctm.17-0039