Contributions of the C-terminal domain to poly(A)-specific ribonuclease (PARN) stability and self-association

Poly(A)-specific ribonuclease (PARN) catalyzes the degradation of mRNA poly(A) tail to regulate translation efficiency and mRNA decay in higher eukaryotic cells. The full-length PARN is a multi-domain protein containing the catalytic nuclease domain, the R3H domain, the RRM domain and the C-terminal...

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Detalles Bibliográficos
Autores principales: He, Guang-Jun, Yan, Yong-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430076/
https://www.ncbi.nlm.nih.gov/pubmed/30949591
http://dx.doi.org/10.1016/j.bbrep.2019.100626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430076/
https://www.ncbi.nlm.nih.gov/pubmed/30949591
http://dx.doi.org/10.1016/j.bbrep.2019.100626

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