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Contributions of the C-terminal domain to poly(A)-specific ribonuclease (PARN) stability and self-association
Poly(A)-specific ribonuclease (PARN) catalyzes the degradation of mRNA poly(A) tail to regulate translation efficiency and mRNA decay in higher eukaryotic cells. The full-length PARN is a multi-domain protein containing the catalytic nuclease domain, the R3H domain, the RRM domain and the C-terminal...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430076/ https://www.ncbi.nlm.nih.gov/pubmed/30949591 http://dx.doi.org/10.1016/j.bbrep.2019.100626 |