A dinuclear ruthenium(ii) phototherapeutic that targets duplex and quadruplex DNA

With the aim of developing a sensitizer for photodynamic therapy, a previously reported luminescent dinuclear complex that functions as a DNA probe in live cells was modified to produce a new iso-structural derivative containing Ru(II)(TAP)(2) fragments (TAP = 1,4,5,8-tetraazaphenanthrene). The stru...

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Detalles Bibliográficos
Autores principales: Archer, Stuart A., Raza, Ahtasham, Dröge, Fabian, Robertson, Craig, Auty, Alexander J., Chekulaev, Dimitri, Weinstein, Julia A., Keane, Theo, Meijer, Anthony J. H. M., Haycock, John W., MacNeil, Sheila, Thomas, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430095/
https://www.ncbi.nlm.nih.gov/pubmed/30996941
http://dx.doi.org/10.1039/c8sc05084h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430095/
https://www.ncbi.nlm.nih.gov/pubmed/30996941
http://dx.doi.org/10.1039/c8sc05084h

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