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A dinuclear ruthenium(ii) phototherapeutic that targets duplex and quadruplex DNA
With the aim of developing a sensitizer for photodynamic therapy, a previously reported luminescent dinuclear complex that functions as a DNA probe in live cells was modified to produce a new iso-structural derivative containing Ru(II)(TAP)(2) fragments (TAP = 1,4,5,8-tetraazaphenanthrene). The stru...
Autores principales: | Archer, Stuart A., Raza, Ahtasham, Dröge, Fabian, Robertson, Craig, Auty, Alexander J., Chekulaev, Dimitri, Weinstein, Julia A., Keane, Theo, Meijer, Anthony J. H. M., Haycock, John W., MacNeil, Sheila, Thomas, James A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430095/ https://www.ncbi.nlm.nih.gov/pubmed/30996941 http://dx.doi.org/10.1039/c8sc05084h |
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