Pediatric Dosing of Ganciclovir and Valganciclovir: How Model‐Based Simulations Can Prevent Underexposure and Potential Treatment Failure

Intravenous ganciclovir and oral valganciclovir are effective in the prevention and treatment of pediatric cytomegalovirus (CMV) infection but various dosing regimens are used in medical practice. Population pharmacokinetic (PopPK) model‐based simulations were used to propose a new ganciclovir pedia...

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Detalles Bibliográficos
Autores principales: Jorga, Karin, Reigner, Bruno, Chavanne, Clarisse, Alvaro, Giuseppe, Frey, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430157/
https://www.ncbi.nlm.nih.gov/pubmed/30354026
http://dx.doi.org/10.1002/psp4.12363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430157/
https://www.ncbi.nlm.nih.gov/pubmed/30354026
http://dx.doi.org/10.1002/psp4.12363

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