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Pediatric Dosing of Ganciclovir and Valganciclovir: How Model‐Based Simulations Can Prevent Underexposure and Potential Treatment Failure
Intravenous ganciclovir and oral valganciclovir are effective in the prevention and treatment of pediatric cytomegalovirus (CMV) infection but various dosing regimens are used in medical practice. Population pharmacokinetic (PopPK) model‐based simulations were used to propose a new ganciclovir pedia...
Autores principales: | Jorga, Karin, Reigner, Bruno, Chavanne, Clarisse, Alvaro, Giuseppe, Frey, Nicolas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430157/ https://www.ncbi.nlm.nih.gov/pubmed/30354026 http://dx.doi.org/10.1002/psp4.12363 |
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