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Integrative Omics Reveals Metabolic and Transcriptomic Alteration of Nonalcoholic Fatty Liver Disease in Catalase Knockout Mice

The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased with the incidence of obesity; however, the underlying mechanisms are unknown. In this study, high-resolution metabolomics (HRM) along with transcriptomics were applied on animal models to draw a mechanistic insight of NAFLD. W...

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Detalles Bibliográficos
Autores principales: Na, Jinhyuk, Choi, Soo An, Khan, Adnan, Huh, Joo Young, Piao, Lingjuan, Hwang, Inah, Ha, Hunjoo, Park, Youngja H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430223/
https://www.ncbi.nlm.nih.gov/pubmed/30630288
http://dx.doi.org/10.4062/biomolther.2018.175