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Neuroprotective Effect of β-Lapachone in MPTP-Induced Parkinson’s Disease Mouse Model: Involvement of Astroglial p-AMPK/Nrf2/HO-1 Signaling Pathways

Parkinson’s disease is a neurodegenerative disease characterized by the progressive loss of dopaminergic neurons within the substantia nigra pars compacta. In the present study, we investigated whether β-Lapachone (β-LAP), a natural naphthoquinone compound isolated from the lapacho tree (Tabebuia av...

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Detalles Bibliográficos
Autores principales: Park, Jin-Sun, Leem, Yea-Hyun, Park, Jung-Eun, Kim, Do-Yeon, Kim, Hee-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430227/
https://www.ncbi.nlm.nih.gov/pubmed/30739428
http://dx.doi.org/10.4062/biomolther.2018.234