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Baseline identification of clonal V(D)J sequences for DNA-based minimal residual disease detection in multiple myeloma
Tracking of clonal immunoglobulin V(D)J rearrangement sequences by next generation sequencing is highly sensitive for minimal residual disease in multiple myeloma. However, previous studies have found variable rates of V(D)J sequence identification at baseline, which could limit tracking. Here, we a...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430394/ https://www.ncbi.nlm.nih.gov/pubmed/30901326 http://dx.doi.org/10.1371/journal.pone.0211600 |