Baseline identification of clonal V(D)J sequences for DNA-based minimal residual disease detection in multiple myeloma

Tracking of clonal immunoglobulin V(D)J rearrangement sequences by next generation sequencing is highly sensitive for minimal residual disease in multiple myeloma. However, previous studies have found variable rates of V(D)J sequence identification at baseline, which could limit tracking. Here, we a...

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Detalles Bibliográficos
Autores principales: Rustad, Even H., Hultcrantz, Malin, Yellapantula, Venkata D., Akhlaghi, Theresia, Ho, Caleb, Arcila, Maria E., Roshal, Mikhail, Patel, Akshar, Chen, Denise, Devlin, Sean M., Jacobsen, Austin, Huang, Ying, Miller, Jeffrey E., Papaemmanuil, Elli, Landgren, Ola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430394/
https://www.ncbi.nlm.nih.gov/pubmed/30901326
http://dx.doi.org/10.1371/journal.pone.0211600

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