The paracetamol metabolite N-acetylp-benzoquinone imine reduces excitability in first- and second-order neurons of the pain pathway through actions on K(V)7 channels

Paracetamol (acetaminophen, APAP) is one of the most frequently used analgesic agents worldwide. It is generally preferred over nonsteroidal anti-inflammatory drugs because it does not cause typical adverse effects resulting from the inhibition of cyclooxygenases, such as gastric ulcers. Nevertheles...

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Detalles Bibliográficos
Autores principales: Ray, Sutirtha, Salzer, Isabella, Kronschläger, Mira T., Boehm, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430418/
https://www.ncbi.nlm.nih.gov/pubmed/30601242
http://dx.doi.org/10.1097/j.pain.0000000000001474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430418/
https://www.ncbi.nlm.nih.gov/pubmed/30601242
http://dx.doi.org/10.1097/j.pain.0000000000001474

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