Aptamer‐targeted DNA nanostructures with doxorubicin to treat protein tyrosine kinase 7‐positive tumours

OBJECTIVES: Aptamer sgc8c is a short DNA sequence that can target protein tyrosine kinase 7 (PTK7), which was overexpressed on many tumour cells. This study aimed to fabricate a novelty DNA nanostructure drug delivery system target on PTK7‐positive cells—CCRF‐CEM (human T‐cell ALL). METHODS: Aptamer...

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Detalles Bibliográficos
Autores principales: Liu, Mengting, Ma, Wenjuan, Li, Qianshun, Zhao, Dan, Shao, Xiaoru, Huang, Qian, Hao, Liying, Lin, Yunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430458/
https://www.ncbi.nlm.nih.gov/pubmed/30311693
http://dx.doi.org/10.1111/cpr.12511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430458/
https://www.ncbi.nlm.nih.gov/pubmed/30311693
http://dx.doi.org/10.1111/cpr.12511

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