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Aptamer‐targeted DNA nanostructures with doxorubicin to treat protein tyrosine kinase 7‐positive tumours

OBJECTIVES: Aptamer sgc8c is a short DNA sequence that can target protein tyrosine kinase 7 (PTK7), which was overexpressed on many tumour cells. This study aimed to fabricate a novelty DNA nanostructure drug delivery system target on PTK7‐positive cells—CCRF‐CEM (human T‐cell ALL). METHODS: Aptamer...

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Detalles Bibliográficos
Autores principales:	Liu, Mengting, Ma, Wenjuan, Li, Qianshun, Zhao, Dan, Shao, Xiaoru, Huang, Qian, Hao, Liying, Lin, Yunfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430458/ https://www.ncbi.nlm.nih.gov/pubmed/30311693 http://dx.doi.org/10.1111/cpr.12511

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