Paclitaxel Induce Apoptosis of Giant Cells Tumor of Bone via TP53INP1 Signaling

OBJECTIVE: To evaluate the antitumor capability and to investigate the underlying molecular mechanism of paclitaxel. METHODS: First, cck‐8 and apoptosis assays were used to determine survival and apoptotic effects of HS 737.T cells under treatment of paclitaxel. Next, RNA‐seq and bioinformatics were...

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Detalles Bibliográficos
Autores principales: Xiao, Wei‐Yuan, Zong, Zhen, Qiu, Man‐Le, Chen, Xiu‐Yuan, Shen, Hong‐Xing, Lao, Li‐Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2018
Materias:
Basic Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430463/
https://www.ncbi.nlm.nih.gov/pubmed/30592172
http://dx.doi.org/10.1111/os.12414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430463/
https://www.ncbi.nlm.nih.gov/pubmed/30592172
http://dx.doi.org/10.1111/os.12414

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