Aberrant insulin receptor expression is associated with insulin resistance and skeletal muscle atrophy in myotonic dystrophies

Myotonic dystrophy type 1 (DM1) and type 2 (DM2) are autosomal dominant multisystemic disorders linked to two different genetic loci and characterized by several features including myotonia, muscle atrophy and insulin resistance. The aberrant alternative splicing of insulin receptor (IR) gene and po...

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Detalles Bibliográficos
Autores principales: Renna, Laura Valentina, Bosè, Francesca, Brigonzi, Elisa, Fossati, Barbara, Meola, Giovanni, Cardani, Rosanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430513/
https://www.ncbi.nlm.nih.gov/pubmed/30901379
http://dx.doi.org/10.1371/journal.pone.0214254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430513/
https://www.ncbi.nlm.nih.gov/pubmed/30901379
http://dx.doi.org/10.1371/journal.pone.0214254

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