Effective Suppression of HIV-1 Replication by Cytotoxic T Lymphocytes Specific for Pol Epitopes in Conserved Mosaic Vaccine Immunogens

Cytotoxic T lymphocytes (CTLs) with strong abilities to suppress HIV-1 replication and recognize circulating HIV-1 could be key for both HIV-1 cure and prophylaxis. We recently designed conserved mosaic T-cell vaccine immunogens (tHIVconsvX) composed of 6 Gag and Pol regions. Since the tHIVconsvX va...

Descripción completa

Detalles Bibliográficos
Autores principales: Zou, Chengcheng, Murakoshi, Hayato, Kuse, Nozomi, Akahoshi, Tomohiro, Chikata, Takayuki, Gatanaga, Hiroyuki, Oka, Shinichi, Hanke, Tomáš, Takiguchi, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430542/
https://www.ncbi.nlm.nih.gov/pubmed/30674626
http://dx.doi.org/10.1128/JVI.02142-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430542/
https://www.ncbi.nlm.nih.gov/pubmed/30674626
http://dx.doi.org/10.1128/JVI.02142-18

Ejemplares similares