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Engineering Responses to Amino Acid Substitutions in the VP0- and VP3-Coding Regions of PanAsia-1 Strains of Foot-and-Mouth Disease Virus Serotype O

The presence of sequence divergence through adaptive mutations in the major capsid protein VP1, and also in VP0 (VP4 and VP2) and VP3, of foot-and-mouth disease virus (FMDV) is relevant to a broad range of viral characteristics. To explore the potential role of isolate-specific residues in the VP0 a...

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Detalles Bibliográficos
Autores principales: Bai, Xing-Wen, Bao, Hui-Fang, Li, Ping-Hua, Ma, Xue-Qing, Sun, Pu, Bai, Qi-Feng, Zhang, Meng, Yuan, Hong, Chen, Dong-Dong, Li, Kun, Chen, Ying-Li, Cao, Yi-Mei, Fu, Yuan-Fang, Zhang, Jing, Li, Dong, Lu, Zeng-Jun, Liu, Zai-Xin, Luo, Jian-Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430551/
https://www.ncbi.nlm.nih.gov/pubmed/30700601
http://dx.doi.org/10.1128/JVI.02278-18