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Non-specific degradation of transcripts promotes plasmid clearance during type III-A CRISPR-Cas immunity
Type III-A CRISPR-Cas systems employ the Cas10-Csm complex to destroy bacteriophages and plasmids, using a guide RNA to locate complementary RNA molecules from the invader and trigger an immune response that eliminates the infecting DNA. In addition, these systems possess the non-specific RNase Csm6...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430669/ https://www.ncbi.nlm.nih.gov/pubmed/30692669 http://dx.doi.org/10.1038/s41564-018-0353-x |