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Adolescent exposure to Δ(9)-tetrahydrocannabinol alters the transcriptional trajectory and dendritic architecture of prefrontal pyramidal neurons

Neuronal circuits within the prefrontal cortex (PFC) mediate higher cognitive functions and emotional regulation that are disrupted in psychiatric disorders. The PFC undergoes significant maturation during adolescence, a period when cannabis use in humans has been linked to subsequent vulnerability...

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Detalles Bibliográficos
Autores principales: Miller, Michael L., Chadwick, Benjamin, Dickstein, Dara L., Purushothaman, Immanuel, Egervari, Gabor, Rahman, Tanni, Tessereau, Chloe, Hof, Patrick R., Roussos, Panos, Shen, Li, Baxter, Mark G., Hurd, Yasmin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430678/
https://www.ncbi.nlm.nih.gov/pubmed/30283037
http://dx.doi.org/10.1038/s41380-018-0243-x