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Adolescent exposure to Δ(9)-tetrahydrocannabinol alters the transcriptional trajectory and dendritic architecture of prefrontal pyramidal neurons
Neuronal circuits within the prefrontal cortex (PFC) mediate higher cognitive functions and emotional regulation that are disrupted in psychiatric disorders. The PFC undergoes significant maturation during adolescence, a period when cannabis use in humans has been linked to subsequent vulnerability...
Autores principales: | Miller, Michael L., Chadwick, Benjamin, Dickstein, Dara L., Purushothaman, Immanuel, Egervari, Gabor, Rahman, Tanni, Tessereau, Chloe, Hof, Patrick R., Roussos, Panos, Shen, Li, Baxter, Mark G., Hurd, Yasmin L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430678/ https://www.ncbi.nlm.nih.gov/pubmed/30283037 http://dx.doi.org/10.1038/s41380-018-0243-x |
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