Potassium channel selectivity filter dynamics revealed by single-molecule FRET

Potassium (K) channels exhibit exquisite selectivity for conduction of K(+) ions over other cations, particularly Na(+). High resolution structures reveal an archetypal selectivity filter (SF) conformation in which dehydrated K(+), but not Na(+), ions are perfectly coordinated. Using single molecule...

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Detalles Bibliográficos
Autores principales: Wang, Shizhen, Lee, Sun-Joo, Maksaev, Grigory, Fang, Xin, Zuo, Chong, Nichols, Colin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430689/
https://www.ncbi.nlm.nih.gov/pubmed/30833778
http://dx.doi.org/10.1038/s41589-019-0240-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430689/
https://www.ncbi.nlm.nih.gov/pubmed/30833778
http://dx.doi.org/10.1038/s41589-019-0240-7

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