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Potassium channel selectivity filter dynamics revealed by single-molecule FRET
Potassium (K) channels exhibit exquisite selectivity for conduction of K(+) ions over other cations, particularly Na(+). High resolution structures reveal an archetypal selectivity filter (SF) conformation in which dehydrated K(+), but not Na(+), ions are perfectly coordinated. Using single molecule...
Autores principales: | Wang, Shizhen, Lee, Sun-Joo, Maksaev, Grigory, Fang, Xin, Zuo, Chong, Nichols, Colin G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430689/ https://www.ncbi.nlm.nih.gov/pubmed/30833778 http://dx.doi.org/10.1038/s41589-019-0240-7 |
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