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Simultaneous Photoradiochemical Labeling of Antibodies for Immuno-Positron Emission Tomography
A method for the simultaneous (one-step) photochemical conjugation and (89)Zr-radiolabeling of antibodies is introduced. A photoactivatable chelate based on the functionalization of desferrioxamine B with an arylazide moiety (DFO-ArN(3), [1]) was synthesized. The radiolabeled complex, (89)Zr-1(+), w...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430723/ https://www.ncbi.nlm.nih.gov/pubmed/30903963 http://dx.doi.org/10.1016/j.isci.2019.03.004 |