The selective HDAC6 inhibitor Nexturastat A induces apoptosis, overcomes drug resistance and inhibits tumor growth in multiple myeloma

Multiple myeloma (MM) is a hematological malignancy of plasma cells that produce a monoclonal immunoglobulin protein. Despite significant advances in the treatment of MM, challenges such as resistance to therapy remain. Currently, inhibition of histone deacetylases (HDACs) is emerging as a potential...

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Detalles Bibliográficos
Autores principales: Sun, Xiaoyang, Xie, Yu, Sun, Xiaoshen, Yao, Yao, Li, Hujun, Li, Zhenyu, Yao, Ruosi, Xu, Kailin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430725/
https://www.ncbi.nlm.nih.gov/pubmed/30782785
http://dx.doi.org/10.1042/BSR20181916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430725/
https://www.ncbi.nlm.nih.gov/pubmed/30782785
http://dx.doi.org/10.1042/BSR20181916

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