Application of Magnetic Resonance to Assess Lyophilized Drug Product Reconstitution

PURPOSE: Dynamic in-situ proton ((1)H) magnetic resonance imaging (MRI) and (1)H T(2)-relaxometry experiments are described in an attempt to: (i) understand the physical processes, that occur during the reconstitution of lyophilized bovine serum albumin (BSA) and monoclonal antibody (mAb) proteins;...

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Detalles Bibliográficos
Autores principales: Partridge, Thomas A., Ahmed, Mahammad, Choudhary, Sureshkumar B., van der Walle, Christopher F., Patel, Sajal M., Bishop, Steven M., Mantle, Mick D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430757/
https://www.ncbi.nlm.nih.gov/pubmed/30903389
http://dx.doi.org/10.1007/s11095-019-2591-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430757/
https://www.ncbi.nlm.nih.gov/pubmed/30903389
http://dx.doi.org/10.1007/s11095-019-2591-x

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