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Spatial-fluxomics provides a subcellular-compartmentalized view of reductive glutamine metabolism in cancer cells
The inability to inspect metabolic activities within subcellular compartments has been a major barrier to our understanding of eukaryotic cell metabolism. Here, we describe a spatial-fluxomics approach for inferring metabolic fluxes in mitochondria and cytosol under physiological conditions, combini...
Autores principales: | Lee, Won Dong, Mukha, Dzmitry, Aizenshtein, Elina, Shlomi, Tomer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430770/ https://www.ncbi.nlm.nih.gov/pubmed/30903027 http://dx.doi.org/10.1038/s41467-019-09352-1 |
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