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Notch1 promotes the pericyte-myofibroblast transition in idiopathic pulmonary fibrosis through the PDGFR/ROCK1 signal pathway

The goals of this study were to investigate the role of the Notch1/PDGFRβ/ROCK1 signaling pathway in the pathogenesis of pulmonary fibrosis and to explore the possibility of treating fibrosis by targeting Notch1. Lung tissues from patients with pulmonary fibrosis were examined for the expression of...

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Detalles Bibliográficos
Autores principales: Wang, Yi-Chun, Chen, Qiong, Luo, Jun-Ming, Nie, Jing, Meng, Qing-He, Shuai, Wei, Xie, Han, Xia, Jia-Mei, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430797/
https://www.ncbi.nlm.nih.gov/pubmed/30902967
http://dx.doi.org/10.1038/s12276-019-0228-0