Chiral DNA sequences as commutable controls for clinical genomics

Chirality is a property describing any object that is inequivalent to its mirror image. Due to its 5′–3′ directionality, a DNA sequence is distinct from a mirrored sequence arranged in reverse nucleotide-order, and is therefore chiral. A given sequence and its opposing chiral partner sequence share...

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Detalles Bibliográficos
Autores principales: Deveson, Ira W., Madala, Bindu Swapna, Blackburn, James, Barker, Chris, Wong, Ted, Barton, Kirston M., Smith, Martin A., Watkins, D. Neil, Mercer, Tim R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430799/
https://www.ncbi.nlm.nih.gov/pubmed/30902988
http://dx.doi.org/10.1038/s41467-019-09272-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430799/
https://www.ncbi.nlm.nih.gov/pubmed/30902988
http://dx.doi.org/10.1038/s41467-019-09272-0

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