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Ubiquitination of MAP1LC3B by pVHL is associated with autophagy and cell death in renal cell carcinoma

Von Hippel Lindau (VHL) expression is significantly decreased in high-grade RCC, and autophagy, which is involved in tumor growth, invasion, differentiation, and metastasis, is activated in various human cancers. However, the relationship of autophagy and VHL in tumor progression remains controversi...

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Detalles Bibliográficos
Autores principales: Kang, Hyun Mi, Noh, Kyung Hee, Chang, Tae Kyung, Park, Dongmin, Cho, Hyun-Soo, Lim, Jung Hwa, Jung, Cho-Rok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430800/
https://www.ncbi.nlm.nih.gov/pubmed/30902965
http://dx.doi.org/10.1038/s41419-019-1520-6