Deacetylation of CHK2 by SIRT1 protects cells from oxidative stress-dependent DNA damage response

Growing evidence indicates that metabolic signaling pathways are interconnected to DNA damage response (DDR). However, factors that link metabolism to DDR remain incompletely understood. SIRT1, an NAD(+)-dependent deacetylase that regulates metabolism and aging, has been shown to protect cells from...

Descripción completa

Detalles Bibliográficos
Autores principales: Kwon, Jiyun, Lee, Suhee, Kim, Yong-Nyun, Lee, In Hye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430805/
https://www.ncbi.nlm.nih.gov/pubmed/30902968
http://dx.doi.org/10.1038/s12276-019-0232-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430805/
https://www.ncbi.nlm.nih.gov/pubmed/30902968
http://dx.doi.org/10.1038/s12276-019-0232-4

Ejemplares similares