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Allele-specific binding of RNA-binding proteins reveals functional genetic variants in the RNA

Allele-specific protein-RNA binding is an essential aspect that may reveal functional genetic variants (GVs) mediating post-transcriptional regulation. Recently, genome-wide detection of in vivo binding of RNA-binding proteins is greatly facilitated by the enhanced crosslinking and immunoprecipitati...

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Detalles Bibliográficos
Autores principales: Yang, Ei-Wen, Bahn, Jae Hoon, Hsiao, Esther Yun-Hua, Tan, Boon Xin, Sun, Yiwei, Fu, Ting, Zhou, Bo, Van Nostrand, Eric L., Pratt, Gabriel A., Freese, Peter, Wei, Xintao, Quinones-Valdez, Giovanni, Urban, Alexander E., Graveley, Brenton R., Burge, Christopher B., Yeo, Gene W., Xiao, Xinshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430814/
https://www.ncbi.nlm.nih.gov/pubmed/30902979
http://dx.doi.org/10.1038/s41467-019-09292-w