Effects of the potassium‐sparing diuretic amiloride on chemotherapy response in canine osteosarcoma cells

BACKGROUND: Osteosarcoma (OSA) is a common bone tumor of mesenchymal origin in dogs. Chemotherapy delays metastasis, yet most dogs die of this disease within 1 year of diagnosis. The high metabolic demand of cancer cells promotes proton pump upregulation, leading to acidification of the tumor microe...

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Detalles Bibliográficos
Autores principales: Poon, Andrew C., Inkol, Jordon M., Luu, Anita K., Mutsaers, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
SMALL ANIMAL
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430882/
https://www.ncbi.nlm.nih.gov/pubmed/30556178
http://dx.doi.org/10.1111/jvim.15382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430882/
https://www.ncbi.nlm.nih.gov/pubmed/30556178
http://dx.doi.org/10.1111/jvim.15382

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