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Pharmacokinetics and pharmacodynamics of intravenous esomeprazole at 2 different dosages in dogs

BACKGROUND: Although the demand for esomeprazole is increasing in veterinary medicine, the pharmacokinetics (PK) and pharmacodynamics of esomeprazole have been described in only a few studies. OBJECTIVE: To determine the PK of 0.5 and 1 mg/kg esomeprazole administered IV q12h and to investigate its...

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Detalles Bibliográficos
Autores principales: Seo, Do‐Hyun, Lee, Jong‐Bok, Hwang, Ji‐Hye, Jeong, Jong‐Woo, Song, Gun‐Ho, Koo, Tae‐Sung, Seo, Kyoung‐Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430889/
https://www.ncbi.nlm.nih.gov/pubmed/30548689
http://dx.doi.org/10.1111/jvim.15383