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Enzyme kinetics of dUTPase from the planarian Dugesia ryukyuensis

OBJECTIVE: Planarians including Dugesia ryukyuensis (Dr) have strong regenerative abilities that require enhanced DNA replication. Knockdown of the DUT gene in Dr, which encodes deoxyuridine 5′-triphosphate pyrophosphatase (dUTPase), promotes DNA fragmentation, inhibits regeneration, and eventually...

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Detalles Bibliográficos
Autores principales: Alam, Md. Shahanoor, Moriyama, Hideaki, Matsumoto, Midori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431053/
https://www.ncbi.nlm.nih.gov/pubmed/30902068
http://dx.doi.org/10.1186/s13104-019-4191-6