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Enzyme kinetics of dUTPase from the planarian Dugesia ryukyuensis
OBJECTIVE: Planarians including Dugesia ryukyuensis (Dr) have strong regenerative abilities that require enhanced DNA replication. Knockdown of the DUT gene in Dr, which encodes deoxyuridine 5′-triphosphate pyrophosphatase (dUTPase), promotes DNA fragmentation, inhibits regeneration, and eventually...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431053/ https://www.ncbi.nlm.nih.gov/pubmed/30902068 http://dx.doi.org/10.1186/s13104-019-4191-6 |